| Fluticasone furoate nasal spray | |
|---|---|
| Drug Indication | Prophylaxis and treatment of seasonal and perennial allergic rhinitis and hay fever |
| Precautions | Treatment of the infections of the nose and pharynx before using this medicine; gradual withdrawal of exogenous steroids; transfer of patients from systemic steroid treatment; nasal trauma; recent nasal surgery. |
| Contra-Indications | History of recurrent nasal bleeding; untreated bacterial/viral/fungal infections; children under 6yrs; unhealed nasal wound; pregnancy. |
| Side Effects | Epistaxis; nasal septum perforation; unpleasant taste and smell; glaucoma; increase IOP; haemorrhagic nasal discharge; stuffy nose; local candidal infections |
| Dosage | Children 4-11yrs: inhale into each nostril once daily, increased to twice daily (max. 4 sprays daily). Adults and children over 12yrs: inhale two sprays once daily to a max. of 8 sprays daily. |
| Drug Category | DRUGS ACTING ON ENT |
| Drug Sub-Category | Steroid hormones and related synthetic drugs |
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Avamys | GSK Ltd. | 27.5mcg | Spray -120doses | KES 853 | |||
| Fluticasone propionate inhaler | |
|---|---|
| Mode Of Action | Corticosteroids activity involve inhibition of various process that are involved in the inflammation e.g. inhibition of secretion of growth factors, endothelial activating and other cytokines from lymphocytes, eosinophils, macrophages, fibroblasts, and mast cells. The net effect is to reduce the chronic inflammation in asthmatic airways. |
| Drug Indication | Prevention of bronchial asthma (not for acute attack) not well controlled by the bronchodilators |
| Precautions | Active pulmonary TB; airways obstruction; times of stress; gradual withdrawal of systematic steroid therapy; respiratory infections. |
| Contra-Indications | Status asthmaticus; safety in pregnancy and lactation not yet fully established; acute asthma attack; untreated airways infections; recurrent nasal bleeding. |
| Side Effects | Throat candidiasis; hoarseness of the voice; throat irritation; paradoxical bronchospasm (discontinue); adrenal suppression; cataract formation after prolonged use; cutaneous hypersensitivity reactions; cough and sneeze due to irritation; pulmonary infiltrates. |
| Dosage | Adult and children over 16yrs; 100-1000mg BD: Children over 6 years; 50-100mg BD. |
| Pregnancy Category | Category B3 |
| Pregnancy Category Description | Drugs which have been taken by only a small number of pregnant women and women of child-bearing age with no any established rise in the frequency of malformations or other direct or indirect detrimental effects on the foetus having been noted. Studies in animals show evidence of an increased occurrence of foetal damage, the significance of which is uncertain in human |
| Drug Category | DRUGS ACTING ON RESPIRATORY SYSTEM |
| Drug Sub-Category | Inhalers |
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Flixotide | GlaxoSmithkline | GlaxoSmithKline | 50mcg | 120 doses | inhaler | per actuation | KES 581.70 |
| Flixotide | GlaxoSmithkline | GlaxoSmithKline | 0.125mg | 120 doses | inhaler | per actuation | KES 1,169.30 |
| Flixotide | GlaxoSmithkline | GlaxoSmithKline | 0.25mg | 120 doses | inhaler | per actuation | KES 1,351.50 |
| Fluticasone propionate nasal spray | |
|---|---|
| Drug Indication | Prophylaxis and treatment of seasonal and perennial allergic rhinitis and hay fever |
| Precautions | Treatment of the infections of the nose and pharynx before using this medicine; gradual withdrawal of exogenous steroids; transfer of patients from systemic steroid treatment; nasal trauma; recent nasal surgery. |
| Contra-Indications | History of recurrent nasal bleeding; untreated bacterial/viral/fungal infections; children under 6yrs; unhealed nasal wound; pregnancy. |
| Side Effects | Epistaxis; nasal septum perforation; unpleasant taste and smell; glaucoma; increase IOP; haemorrhagic nasal discharge; stuffy nose; local candidal infections |
| Dosage | Children 4-11yrs: inhale into each nostril once daily, increased to twice daily (max. 4 sprays daily). Adults and children over 12yrs: inhale two sprays once daily to a max. of 8 sprays daily. |
| Drug Category | DRUGS ACTING ON ENT |
| Drug Sub-Category | Steroid hormones and related synthetic drugs |
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Fixonase | GSK Ltd. | 50mcg/spray | 120 doses | KES 700 | |||
| Flonaspray | Square | 50mcg/spray | 120 doses | KES 700 |